Set the Thames on Fire follows struggling piano player Art (Michael Winder) and compulsive liar Sal (Max Bennett) as they embark on a string of ludicrous escapades through a dystopian London, ruled over by a grotesque and tyrannical Impresario. 　　On their adventures they encounter a deranged Magician, played by performance artist David Hoyle, an anarchist witch (Phillips) and the Impresario’s twisted right-hand man (Fielding) leading to a final showdown with the despotic ruler himself.